Pharmaceutical Pipeline

The table below shows a selection of key drugs in late stages of development or pending registration in the U.S. by one of our operating companies. This list is not meant to be exhaustive, and the products shown here are intended for use by patients in the U.S. only. Some of these products may already be marketed in countries outside the U.S., or may be under consideration for development in other countries.

Selected Pharmaceuticals in Late Stage Development or Pending Registration:
As of October 14th, 2003*

Product Name   Indication
 
 
Central Nervous System  
   
REMINYL® (galantamine) - Janssen Pharmaceutica Products, L.P. Mild cognitive impairment; Extended release capsule
   
RISPERDAL® (risperidone) - Janssen Pharmaceutica Products, L.P. Psychosis in Alzheimer's Dementia
   
RISPERDAL® CONSTA (risperidone) - Janssen Pharmaceutica Products, L.P. Schizophrenia - IM long acting injectable (1); Bipolar mania; Pediatric; Autism
   
TOPAMAX® (topiramate) - Ortho-McNeil Pharmaceutical, Inc. Monotherapy; Migraine prophylaxis
   
CONCERTA® (OROS methylphenidate) - Ortho-McNeil Pharmaceutical, Inc. Adult attention deficit hyperactivity disorder
   
Gastrointestinal  
   
REMICADE® (infliximab) - Centocor, Inc. Ulcerative Colitis; Pediatric Crohn's
   
Auto-immune Disease  
   
REMICADE® (infliximab) - Centocor, Inc. Juvenile RA; Early RA; Psoriasis; Psoriatic Arthritis; Ankylosing Spondylitis
   
Hematology  
   
PROCRIT® (Epoetin Alfa) - Ortho Biotech Products, L.P. 1X wk dosing for anemia associated with cancer chemotherapy; Anemia in critically ill patients
   
Infectious Disease  
   
LEVAQUIN® (levofloxacin) - Ortho-McNeil Pharmaceutical, Inc. 750 mg short course CAP; 750 mg short course sinusitis; 750 mg short course bronchitis; Oral solution (bacterial infections)
   
Oncology  
   
DOXIL® (doxorubicin HCl liposome injection) - Ortho Biotech Products, L.P Multiple Myeloma
   
Pain Management  
   
E TRANS® (fentanyl) - ALZA Corporation Acute, post-operative pain
   
ULTRACET™ (tramadol/APAP) - Ortho-McNeil Pharmaceutical, Inc. Chronic pain management; Liquid formulation
   
AP 48 (next generation DURAGESIC®) - ALZA Corporation Chronic, severe pain
   
Cardiovascular  
   
ReoPro® (abciximab) - Centocor, Inc. Facilitated Percutaneous Coronary Intervention (PCI)
   
Reproductive Health  
   
Dapoxetine - ALZA Corporation Premature or rapid ejaculation
   
 
* This information is accurate as of the date hereof to the best of the Company's knowledge. Johnson & Johnson assumes no obligation to update this information.
(1) Collaboration with Alkermes, Inc.
 
 
 
 
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Janssen-Cilag is a leading research-based pharmaceutical company, with more than 19,000 employees world-wide and establishments in about 50 countries. In India, Janssen-
 
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